Significant studies on the effects of microplastics on the human body are limited partly because it is difficult to identify a true control group unexposed to microplastics.
Terrifying fact: they can’t do any significant studies on the effects of microplastics on the body because there is…. no. control. group.

Microplastics are in our bodies. Here's why we don't know the health risks
Source: sciencenews.org
Key Evidence
Microplastics are pervasive in human environments and bodies, making it difficult to find unexposed individuals for control groups in health studies.
washingtonpost.comwashingtonpost.comMicroplastics are everywhere. Why don’t we know what they do to our health?
pubs.acs.orgpubs.acs.orgPotential Health Impact of Microplastics: A Review of Environmental... Current research relies heavily on small sample sizes and experimental models rather than large epidemiological studies.
What the Evidence Shows
The claim asserts that researchers cannot conduct significant studies on microplastics' effects on the body due to the absence of a control group. This is largely accurate. Microplastics are now ubiquitous in the environment, food, air, and water, making it nearly impossible to find humans completely unexposed to them for comparison purposes.washingtonpost.comwashingtonpost.comMicroplastics are everywhere. Why don’t we know what they do to our health?
pubs.acs.orgpubs.acs.orgPotential Health Impact of Microplastics: A Review of Environmental...
Epidemiological studies with large populations linking exposure levels to health outcomes are currently lacking, partly because everyone has some level of exposure, which complicates establishing a baseline or control group.pubs.acs.orgpubs.acs.orgPotential Health Impact of Microplastics: A Review of Environmental... Experimental models often rely on animal or cell culture studies rather than human trials, limiting direct conclusions about human health impacts.
However, research is ongoing to understand exposure levels and potential toxic effects, and some studies have identified possible mechanisms of harm such as oxidative stress and DNA damage in model systems. The claim's framing as a 'terrifying fact' is subjective and somewhat sensationalized, but the core scientific challenge regarding control groups and study design is valid. Alternative approaches such as dose-response assessments and biomonitoring are being explored to overcome these limitations.
Thus, while it is not impossible to study microplastics' effects, the lack of a true unexposed control group in humans is a significant methodological hurdle that limits definitive conclusions at present.