Excessive intake of fructose from sources like table sugar, high-fructose corn syrup, and processed foods is associated with an increased risk of developing kidney stones.
Too much fructose -- from table sugar, high-fructose corn syrup, or processed foods -- raises your chances for kidney stones.

Fructose consumption and the risk of kidney stones - ScienceDirect
Source: sciencedirect.com
Key Evidence
Multiple peer-reviewed studies demonstrate that high fructose intake increases urinary components that promote kidney stones. Epidemiological data show a clear independent association between fructose consumption from sugar and high-fructose corn syrup and increased kidney stone risk.
What the Evidence Shows
The claim that consuming too much fructose raises the chances of kidney stones is supported by multiple epidemiological and clinical studies. Fructose, a component of table sugar (sucrose) and high-fructose corn syrup, has been shown to increase urinary excretion of calcium, oxalate, and uric acid, key factors in kidney stone formation.ncbi.nlm.nih.govncbi.nlm.nih.govFructose increases risk for kidney stones: potential role in metabolic syndrome...
sciencedirect.comsciencedirect.comFructose consumption and the risk of kidney stones Several cohort studies have found that fructose intake independently correlates with a higher incidence of kidney stones, even when controlling for other dietary factors.
sciencedirect.comsciencedirect.comFructose consumption and the risk of kidney stones
The biological mechanism involves fructose metabolism leading to changes in urine composition that favor stone formation, such as lowering urinary pH and increasing stone-forming substances. Additionally, processed foods and sugary drinks containing high-fructose corn syrup contribute significantly to overall fructose consumption and thus to this risk.health.harvard.eduhealth.harvard.eduStudy links a sugar-heavy diet to a higher risk of kidney stones While natural fruits contain fructose, they also provide citrate which inhibits stone formation, making processed fructose sources more problematic.
ncbi.nlm.nih.govncbi.nlm.nih.govFructose increases risk for kidney stones: potential role in metabolic syndrome...
Recent studies including a 2023 Harvard Health report confirm that diets high in added sugars substantially increase kidney stone risk. Alternative explanations such as other dietary or genetic factors do not negate the independent association found between fructose and stones.
Therefore, the claim is accurate and well-supported by current scientific evidence.