California is actively planning to create its own state-level National Institutes of Health–style research institute to offset significant federal cuts to science funding.
California is devising a plan to create their own National Institutes of Health to counter federal cuts to science research.

California eyes its own National Institutes of Health as science funding faces deep federal cuts - ABC7 Los Angeles
Source: abc7.com
Key Evidence
ABC7 Los Angeles and KTVU FOX 2 report on California's plan for a new institute covering biomedicine, climate change, and vaccine research.
The New York Times details a $23 billion bond plan by California lawmakers to restore scientific research funding lost at the federal level.
University of California sources highlight opposition to federal NIH cuts and support for state-led initiatives.
Additional reports from NewKerala.com and Prokerala.com confirm legislative moves toward creating this institute.
What the Evidence Shows
Multiple independent sources from September 2025 confirm that California is developing a plan to establish the California Institute for Scientific Research (CISR), a state agency designed to fund and conduct scientific research across various fields including biomedicine, climate change, drug safety, vaccines, and emerging health threats. This initiative is a direct response to deep federal budget cuts to the National Institutes of Health (NIH) and other science funding programs under recent federal administrations.
The plan includes authorizing grants and loans for both public and private research entities and aims to restore scientific leadership and innovation within the state. California lawmakers are proposing a substantial financial commitment, including a $23 billion bond measure, to support this effort. The initiative has broad support from academic institutions such as the University of California, which also opposes federal NIH funding cuts through legal actions.
While the proposal is ambitious and still in development, the evidence clearly shows California's intent to create a state-level NIH equivalent to counteract federal funding reductions.