The claim that President Trump issued a memo calling for government-wide 'terrorism investigations' into political opponents is false because available sources, including a recent New York Times article, do not report any such memo or directive; instead, they discuss his declarations about groups like Antifa without evidence of targeting political opponents broadly.
President Trump issued a memo calling for government-wide "terrorism investigations" into political opponents.

FactVerify
Source: factverify.com
Key Evidence
The New York Times article discusses Trump's declarations about Antifa but does not mention any memo or directive for terrorism investigations into political opponents. No other sources corroborate the existence of such a memo or government-wide investigation order.
What the Evidence Shows
The search results and the provided source focus on President Trump's declarations regarding designating groups such as Antifa as terrorist organizations. The New York Times article from September 18, 2025, mentions that Trump made a similar declaration in 2020 but that it did not result in substantive action. The article also notes the context of broader threats against liberals but does not mention any official memo or government-wide order to investigate political opponents under terrorism statutes.
There is no evidence in the source or search results indicating that President Trump has issued a formal memo directing terrorism investigations specifically targeting his political opponents. Therefore, the claim lacks factual support based on current available information.