Immune cells such as macrophages do physically interact with other human cells to promote healing, similar to the role zebrafish macrophages play in tissue regeneration.
Immune cells physically interact with or can touch other human cells to promote the healing process in similar wasy like the zebrafish macrophage

The Phagocytic Function of Macrophage-Enforcing Innate Immunity and Tissue Homeostasis - PMC
Source: pmc.ncbi.nlm.nih.gov
Key Evidence
Macrophages phagocytose damaged cells and secrete mediators that regulate inflammation and tissue repair.
pmc.ncbi.nlm.nih.govpmc.ncbi.nlm.nih.govThe Phagocytic Function of Macrophage-Enforcing Innate Immunity and Tissue...
Zebrafish macrophages have been shown to play a critical role in injury and tissue regeneration through direct cellular interactions.
frontiersin.orgfrontiersin.orgFrontiers - The Role of Macrophages During Zebrafish Injury and Tissue...
Human macrophages also present antigens and release cytokines that activate other immune cells, facilitating coordinated healing responses.
immunology.orgimmunology.orgMacrophages
What the Evidence Shows
Macrophages are a key component of the innate immune system in humans and are known to physically interact with other cells during the healing process. They perform functions such as phagocytosis of damaged cells and pathogens, secretion of cytokines to modulate inflammation, and presentation of antigens to activate adaptive immunity. These interactions facilitate tissue repair and homeostasis.
In zebrafish, macrophages have been extensively studied for their role in injury response and tissue regeneration, where they also physically contact other cells to promote healing. While the exact mechanisms may vary between species, the fundamental concept that macrophages engage in direct cellular interactions to support tissue repair is conserved.
Therefore, the claim that immune cells can physically touch other human cells to promote healing in a manner similar to zebrafish macrophages is supported by current immunological understanding.